USP Reference Standards -B, chemical structure, molecular formula, Reference Standards

USP Bacampicillin Hydrochloride RS— Do not dry.Keep container tightly closed.

USP Bacitracin Zinc RS— Dry portion in vacuum at a pressure not exceeding 5mm of mercury at 60

for 3hours before using.Keep container tightly closed.Protect from light.Store in a cold place.

USP Baclofen RS— Do not dry;determine the water content titrimetrically at time of use.Keep container tightly closed.

USP Baclofen Related Compound A RS [4-(4-chlorophenyl)-2-pyrrolidinone] (C10H10ClNO

195.65) —Do not dry before using.Keep container tightly closed,protect from light,and store in a desiccator.

USP Beclomethasone Dipropionate RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.

USP Bendroflumethiazide RS— Dry portion over silica gel for 4hours before using.Keep container tightly closed.

USP Benoxinate Hydrochloride RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.

USP Benzalkonium Chloride RS— After opening ampul,store in a tightly closed container.

USP Benzocaine RS— Dry portion over phosphorus pentoxide for 3hours before using.Keep container tightly closed.

USP Benzoic Acid RS— Dry portion over silica gel for 3hours before using.Keep container tightly closed.

USP Benzonatate RS— Do not dry.After opening ampul,store in a tightly closed,light-resistant container.

USP1,4-Benzoquinone RS— Do not dry before using.Keep container tightly closed and store in a refrigerator,protected from light.Sonication may be necessary to dissolve the material.

USP Benzothiadiazine Related Compound A RS [4-amino-6-chloro-1,3-benzenedisulfonamide] (C6H8ClN3O4S2

285.73) —Keep container tightly closed and protected from light.Dry portion over silica gel for 4hours before using.

USP Benztropine Mesylate RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.

USP Benzyl Alcohol RS— Do not dry before using.Store under an inert gas (nitrogen or argon)atmosphere,between 2

and 8

.Keep container tightly closed.Protect from light.

USP Benzyl Benzoate RS— Do not dry.After opening the ampul,store in a tightly closed container,protected from light.

USP1-Benzyl-3-methyl-5-aminopyrazole Hydrochloride RS (C11H13N3·HCl

223.71) —Keep container tightly closed and protected from light.Dry portion over silica gel for 4hours before using.

USP Betaine Hydrochloride RS— Do not dry.Keep container tightly closed.

USP Betamethasone RS— Do not dry.Keep container tightly closed.

USP Betamethasone Acetate RS— Do not dry;determine the water content titrimetrically at time of use.Keep container tightly closed.

USP Betamethasone Benzoate RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.

USP Betamethasone Dipropionate RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.

USP Betamethasone Sodium Phosphate RS— Determine the water content titrimetrically at time of use.Keep container tightly closed.Store in a dry place.[NOTE—This material is hygroscopic.]

Change to read:

USP Betamethasone Valerate RS—

Do not dry.

USP28Keep container tightly closed.

USP Betaxolol Hydrochloride RS— Dry portion in vacuum at 65

for 2hours before using.Keep container tightly closed.

Change to read:

USP Bethanechol Chloride RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.

The dried material is hygroscopic.After drying,immediately transfer the material to a desiccator.

USP28

USP Bile Salts RS— Dry portion at 105

for 4hours before using.Keep container tightly closed.[Caution—Avoid inhaling airborne particles. ]

Change to read:

USP Positive Bioreaction RS—

Exercise care in handling.Prepare samples as directed in the respective USP General Test Chapters.

USP28

USP Biotin RS— Do not dry before using.Keep container tightly closed.

USP Biperiden RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.Protect from light.

USP Biperiden Hydrochloride RS— Dry portion at 105

for 3hours.Keep container tightly closed and protected from light.

USP Bisacodyl RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.

USP Bis(2-ethylhexyl)Maleate RS (C20H36O4

340.51) —Do not dry before using.Keep container tightly closed.

USP4,4¢-Bis[1,2,3,6-tetrahydro-4-(2-oxo-1-benzimidazolinyl)-1-pyridyl]butyrophenone RS (C34H34N6O3

574.69) —Keep container tightly closed and protected from light.Dry portion in vacuum at 70

for 4hours before using.Unstable material.

USP Bismuth Citrate RS— Do not dry.Keep container tightly closed and protected from light.

USP Bismuth Subsalicylate RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.

USP Bisoprolol Fumarate RS.

USP Bleomycin Sulfate RS— Dry portion in vacuum at a pressure not exceeding 5mm of mercury at room temperature for 3hours in a desiccator containing phosphorous pentoxide before using.Store in a freezer,protected from light,and allow to attain room temperature before opening.This material is very hygroscopic.

USP Bretylium Tosylate RS— Dry portion in vacuum at 75

for 2hours before using.Keep container tightly closed.

USP Brinzolamide RS— Do not dry.Keep container tightly closed.Store in a freezer.

USP Brinzolamide Related Compound A RS [brinzolamide (S)-isomer] (C12H21N3O5S3

383.52) —Do not dry.Keep container tightly closed.Store in a freezer.

USP Brinzolamide Related Compound B RS [(R-4-amino)-2,3-dihydro-2-(3-methoxypropyl)-4H-thieno[3,2,-e]-thiazine-6-sulfonamide-1,1-dioxide ethandioate 1:1] (C10H17N3O5S3·C2H2O4

445.49) —Do not dry.Keep container tightly closed.Store in a freezer.

USP Bromocriptine Mesylate RS— This material is hygroscopic.Determine the volatiles content by TGA,heating a separate 5-10mg portion from 25

to 160

at 10

per minute under nitrogen flowing at about 45mLper minute.Keep container tightly closed,protected from light,and store in a cold place.

USP Bromodiphenhydramine Hydrochloride RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.

USP8-Bromotheophylline RS [8-bromo-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione] (C7H7N4O2Br

259.06) —Do not dry before using.For quantitative applications,determine the water content titrimetrically at the time of use.Keep container tightly closed.

USP Brompheniramine Maleate RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.Protect from light.

USP Bumetanide RS— Do not dry before using.Keep container tightly closed.Protect from light.

USP Bumetanide Related Compound A RS [3-amino-4-phenoxy-5-sulfamoylbenzoic acid] (C13H12N2O5S

308.31) —Do not dry before using.Keep container tightly closed.

USP Bumetanide Related Compound B RS [3-nitro-4-phenoxy-5-sulfamoylbenzoic acid] (C13H10N2O7S

338.29 —Do not dry before using.Keep container tightly closed.

USP Bupivacaine Hydrochloride RS— Do not dry;determine the water content titrimetrically at the time of use.Keep container tightly closed.

USP Buprenorphine Hydrochloride RS— Do not dry before using.Keep container tightly closed and protected from light.

USP Buprenorphine Related Compound A RS [21-[3-(1-propenyl)]-7a-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine] (C29H41NO4

467.65) —Do not dry before using.Keep container tightly closed and protected from light.

USP Bupropion Hydrochloride RS— Do not dry.Keep container tightly closed.Store in a refrigerator.

USP Bupropion Hydrochloride Related Compound A RS [2-(tert-butylamino)-4¢-chloropropiophenone hydrochloride] (C13H18ClNO·HCl

276.21) —Do not dry.

USP Bupropion Hydrochloride Related Compound B RS [2-(tert-butylamino)-3¢-bromopropiophenone hydrochloride] (C13H18BrNO·HCl

320.66) —Do not dry.

USP Bupropion Hydrochloride Related Compound C RS [1-(3-chlorophenyl)-2-hydroxy-1-propanone] (C9H9O2Cl

184.62) —Do not dry.Store at 5

USP Bupropion Hydrochloride Related Compound D RS [2-(tert-butylamino)propiophenone hydrochloride] (C13H19NO·HCl

241.76) —Do not dry.Store at 5

USP Bupropion Hydrochloride Related Compound E RS [1-(3-chlorophenyl)-1,2-propandione] (C9H7O2Cl

182.61) —Do not dry.Store at 5

USP Bupropion Hydrochloride Related Compound F RS [1-(3-chlorophenyl)-1-hydroxy-2-propanone] (C9H9O2

184.62) —Do not dry.

USP Buspirone Hydrochloride RS— Do not dry.After opening,store in a desiccator.Keep container tightly closed and protected from light.Store in a refrigerator.

USP Butabarbital RS— Keep container tightly closed.Dry portion at 105

for 4hours before using.

USP Butalbital RS— Dry portion in vacuum at room temperature to constant weight before using.Keep container tightly closed.

USP Butamben RS— Dry portion over phosphorus pentoxide for 3hours before using.Keep container tightly closed.

USP Butoconazole Nitrate RS— Dry portion in vacuum at 60

for 3hours before using.Keep container tightly closed.Protect from light.

USP Butorphanol Tartrate RS— Do not dry;determine the water content titrimetrically at time of use.Keep container tightly closed.

USP2-tert-Butyl-4-hydroxyanisole RS (C11H16O2

180.25) —Do not dry before using.Keep container tightly closed.Store in a cool place.Protect from light.

USP3-tert-Butyl-4-hydroxyanisole RS (C11H16O2

180.25) —Do not dry before using.Keep container tightly closed.Store in a cool place.Protect from light.

USP Butyl 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoate RS (C21H28N2O5S

420.53) —Do not dry before using.Keep container tightly closed.

USP Butylparaben RS— Do not dry.Keep container tightly closed.