Peppermint
»Peppermint consists of the dried leaf and flowering top of Mentha piperitaLinné(Fam.Labiatae).
Stems and other foreign organic matter á561ñ: not more than 2.0%of stems more than 3mm in diameter and other foreign organic matter.
Botanic characteristics—
Unground peppermint— Leaves,slender stems,and flowering tops.The leaves are opposite,usually more or less crumpled,and frequently detached from the stem.The petiole is from 4mm to 15mm in length,slightly pubescent;the blade,when entire,is ovate-oblong to oblong-lanceolate,from 1.5cm to 9cm in length with an acute apex,a narrowed or rounded base,and a sharply serrate margin;light green to dark green in color;its upper surface is nearly glabrous,its lower surface has a few hairs on the veins and many amber-colored glandular hairs.The stem is quadrangular,from 1mm to 3mm in diameter,glabrous except for a few scattered deflexed hairs,green to dark purple.The flowers occur as a compact,oblong or oval spike of verticillasters,from 1cm to 1.5cm in breadth,rounded at the summit,and in fruit attaining a length of from 3cm to 7cm.The bracts are oblong-lanceolate,from 4mm to 7mm in length;the calyx,tubular-campanulate,equally five-toothed,pubescent,and glandular-punctate,green to dark purple;the corolla is glabrous,light purple,tubular-campanulate,four-cleft,about 3mm in length;stamens,four,short and equal;style two-or rarely three-cleft at the summit.The nutlets are ellipsoidal,about 500µm in diameter.Peppermint has an aromatic,characteristic odor and a pungent taste,and produces a cooling sensation in the mouth.
Histology— Leaf:The lamina is dorsiventral.Both the upper and the lower epidermis consist of epidermal cells with wavy,anticlinal walls and stomata,the latter enclosed by a pair of subsidiary cells whose common wall is at right angles to the guard cells.Many of the epidermal cells,especially over the veins and midrib,bear nonglandular and glandular hairs.The nonglandular hairs,also numerous along the margin,are uniseriate with longitudinally striate and papillose cuticle,up to eight cells in length and tapered to a pointed apex.The glandular hairs occur in two types.The larger of these are sunken in depressions of the epidermis and consist of a one-to two-celled stalk and a glandular head of eight radiating cells beneath the raised cuticle of which volatile oil is secreted.The smaller type of glandular hair consists of a one-to two-celled stalk and a one-celled glandular head containing volatile oil.Beneath the upper epidermis occurs a single layer of palisade parenchyma up to 80µm in length and,directly underneath it,spongy parenchyma of three or four layers of chloroplastid-containing cells,through which zone course the fibrovascular tissues of the veins.
Stem— The stem is quadrangular.It shows a layer of epidermis bearing hairs similar to those of the leaf and possessing cuticularized outer convex walls,a narrow cortex of chlorenchyma,a clear endodermis of tangentially elongated,thin-walled cells with colorless contents,a narrow phloem,a cambium,and a xylem broadest in the regions beneath the stem angles and containing narrow wood-wedges separated by xylem rays one cell in width.The wood-wedges consist chiefly of simple pitted and spiral vessels,tracheids,and wood-fibers.Beneath each of the four angles of the stem occurs an elliptic to ovate zone of collenchyma.Alarge pith composed of thin-walled parenchyma occupies the center.
Powdered Peppermint— Green to light olive green.Shows fragments of leaf epidermis with wavy vertical walls and,if from the lower surface of the leaf,with numerous stomata and glandular and nonglandular hairs,the latter especially numerous along the veins;glandular hairs with a one-to two-celled stalk and one-to eight-celled head,usually set in a depression in the leaf and containing volatile oil and frequently yellowish or brownish crystals which are birefringent;nonglandular hairs with thin,papillose walls and frequently with short,longitudinal striations of one to eight cells and up to 1.4mm in length,the terminal cell pointed or sometimes globular;fragments of chlorenchyma with vascular tissue,the vessels spiral or with simple pits and but slightly lignified;fragments of collenchyma and of thin-walled,nonlignified fibers associated with parenchyma.The pollen grains are spheroidal and smooth.
Auxiliary Information— Staff Liaison:Catherine Sheehan,B.Sc.,Scientist
Expert Committee:(EMC)Excipients:Monograph Content
USP28–NF23Page 3046
Phone Number:1-301-816-8262