»Tetracycline Hydrochloride Oral Suspension contains not less than 2.25g and not more than 2.75g of Tetracycline Hydrochloride in 100mLof Oral Suspension.

Prepare Tetracycline Hydrochloride Oral Suspension as follows (see Pharmaceutical Compounding—Nonsterile Preparations á795ñ):

Dissolve the Dibasic Sodium Phosphate and the Monobasic Sodium Phosphate in 25mLof Purified Water.Separately dissolve an accurately weighed quantity of Cetylpyridinium Chloride in Purified Water and dilute quantitatively,and stepwise if necessary,with Purified Water to obtain 5mLof a solution containing 10mg of Cetylpyridinium Chloride.Mix this solution with 5mLof the aqueous phosphate solution and add the resulting solution,in divided portions,with mixing,to the Tetracycline Hydrochloride in a glass mortar to completely wet the powder,and make a smooth paste.

Transfer the remaining 20mLof the aqueous phosphate solution to a beaker.Using moderate heat,stir to form a vortex,and slowly sprinkle the Xanthan Gum into the vortex to produce a uniform dispersion.Add this dispersion to the paste in the glass mortar,and mix until smooth;then add 20mLof the Suspension Structured Vehicle or Sugar-Free Suspension Vehicle to the mixture.

Dissolve the Sodium Hydroxide in 5mLof Purified Water,and while mixing,slowly add this solution to the prepared mixture.Complete the suspension by adding a sufficient quantity of the Suspension Structured Vehicle or Sugar-Free Suspension Vehicle to make a final volume of 100mL,and pass this final dispersion through a hand homogenizer prior to transferring it to the dispensing container.