Monoethanolamine
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Ethanol,2-amino-.
2-Aminoethanol [141-43-5].
»Monoethanolamine contains not less than 98.0percent and not more than 100.5percent,by weight,of C2H7NO.
Packaging and storage—
Preserve in tight,light-resistant containers.
Specific gravity á841ñ:
between 1.013and 1.016.
Distilling range,Method IIá721ñ—
Not less than 95%of it distills between 167
and 173,a correction factor of 0.052per mm being applied as necessary.
and 173,a correction factor of 0.052per mm being applied as necessary.
Organic volatile impurities,Method Iá467ñ:
meets the requirements.
Residue on ignition á281ñ:
not more than 0.1%.
Assay—
Accurately weigh a glass-stoppered weighing bottle containing 25mLof water.Add 1g of Monoethanolamine,and weigh.Transfer to a suitable flask,add a mixed indicator of 5parts bromocresol green TSand 6parts methyl red TSfor a total of approximately 11parts of solution,mix,and titrate with 0.5Nhydrochloric acid VS.Each mLof 0.5Nhydrochloric acid is equivalent to 30.54mg of C2H7NO.
Auxiliary Information—
Staff Liaison:Catherine Sheehan,B.Sc.,Scientist
Expert Committee:(EMC)Excipients:Monograph Content
USP28–NF23Page 3040
Pharmacopeial Forum:Volume No.28(3)Page 826
Phone Number:1-301-816-8262