Sorbic Acid
;)
2,4-Hexadienoic acid,(E,E)-;2,4-Hexadienoic acid.
(E,E)-Sorbic acid;Sorbic acid [110-44-1].
»Sorbic Acid contains not less than 99.0percent and not more than 101.0percent of C6H8O2,calculated on the anhydrous basis.
Packaging and storage—
Preserve in tight containers,protected from light,and avoid exposure to excessive heat.
Identification—
A:
To a solution of 200mg in 2mLof alcohol add a few drops of bromine TS:the color is discharged.
B:
A1in 400,000solution in isopropyl alcohol exhibits an absorbance maximum at 254±2nm.
and 135
Water,Method Iá921ñ:
not more than 0.5%.
Residue on ignition á281ñ:
not more than 0.2%.
Heavy metals,Method IIá231ñ:
0.001%.
Organic volatile impurities,Method IVá467ñ:
meets the requirements.
Assay—
Dissolve about 250mg of Sorbic Acid,accurately weighed,in a mixture of 50mLof methanol and 25mLof water that previously has been neutralized with 0.02Nsodium hydroxide.Add phenolphthalein TS,and titrate with 0.1Nsodium hydroxide VSto the first pink color that persists for at least 30seconds.Each mLof 0.1Nsodium hydroxide is equivalent to 11.21mg of C6H8O2.
Auxiliary Information—
Staff Liaison:Catherine Sheehan,B.Sc.,Scientist
Expert Committee:(EMC)Excipients:Monograph Content
USP28–NF23Page 3083
Phone Number:1-301-816-8262